

Nutrient Innovations, Inc. is a proud authorized US distributor for Bacillus Coagulans Unique IS-2. Recognized for its safety and extensively documented benefits, Unique IS-2 is a gram-positive, spore-forming probiotic known for its exceptional resilience and scientific validation.


Unique IS-2:
Clinically Proven,
Ultra-Stable Probiotic
Your go-to strain for superior digestive, immune and functional performance in all product formats—no microencapsulation needed.
A Unique Probiotic
Why Bacillus Coagulans Unique IS‑2 Stands Apart from Other Probiotics
Clinically Researched Health Benefits of Bacillus Coagulans Unique IS‑2®


Bacillus Coagulans Unique IS-2:
For Gut Balance
Clinically proven strain to help maintain digestive health.
Digestive Health Reinvented
- Promotes healthy digestion by balancing intestinal flora and improving gut microbiota diversity
- Clinically shown to improve bowel regularity, reduce bloating, and ease abdominal discomfort
- Supports relief from constipation and irregular stools with no reported side effects in trials
Daily Defense with Bacillus Coagulans Unique IS-2
Immune Health Fortification
- Enhances natural immunity by stimulating protective cytokines and immune signaling pathways
- Supports anti-inflammatory responses and improves gut-barrier integrity
- Backed by clinical trials demonstrating improved host resistance to common infections
Bacillus Coagulans Unique IS-2:
Probiotics for Fitness
Empowering Sports Nutrition & Fitness
- Enhances protein absorption with an increase in total plasma-free amino acids for optimal sports nutrition.
- Increase in leg press strength.
- Improvement in vertical jump power.
Bacillus coagulans Unique IS-2® Food Applications
Bacillus coagulans Unique IS‑2® integrates seamlessly into a wide variety of food and supplement applications thanks to its exceptional resilience to heat, pH, and moisture. Whether incorporated into high-temperature baking processes, cold beverages, dairy products, or functional snacks, IS‑2 retains stability without requiring refrigeration or microencapsulation. Its spore-forming nature ensures excellent survivability through manufacturing, storage, and digestion—making it ideal for innovative formulations across health categories.


Baked Goods
Easily incorporated into muffins, cookies, granola bars, and cereals—retains viability through high-temperature baking.


Dairy & Non-Dairy Fermented Products
Compatible with yogurt, cheese, kefir, and plant-based alternatives—supports both live cultures and shelf-stable options.


Functional Beverages
Survives acidic, cold, or hot beverages including juices, smoothies, kombucha, coffee, and tea—without altering taste, aroma, or appearance.


Savory Applications
Compatible with yogurt, cheese, kefir, and plant-based alternatives—supports both live cultures and shelf-stable options.
Bacillus coagulans Unique IS-2® in Nutraceuticals
Bacillus coagulans Unique IS‑2® is a formulation-friendly probiotic ideal for a wide range of nutraceutical applications. Its naturally encapsulated spore structure allows it to survive manufacturing processes, shelf storage, and gastrointestinal transit without the need for refrigeration or protective coatings. This makes it highly compatible with diverse supplement delivery systems including capsules, tablets, powders, gummies, and liquid suspensions. Whether used as a standalone probiotic or combined with complementary ingredients like digestive enzymes, botanicals, or prebiotics, Unique IS‑2 offers reliable stability, clean-label appeal, and science-backed efficacy across consumer health categories.
Capsules & Tablets
Ideal for standalone probiotics or synergistic blends—maintains viability throughout GI transit and shelf life.
Powders & Stick Packs
Perfect for sachets, single-serve powders, and blends with prebiotics or digestive enzymes—easy to mix and consumer-friendly.
Softgels & Gummies
Stable without refrigeration, enabling inclusion in chewables, softgels, and gummies without sensory or stability compromises.
Oral Drops & Suspensions
Well-suited for liquid delivery in pediatric, geriatric, or pet supplements—retains potency in aqueous environments.
Ingredients Synergizing with Bacillus coagulans Unique IS-2®
Probiotic Powerhouses
Nutrient Boosters
Omega-3 Fatty Acids
Herbal Allies
Blend with herbal extracts like chamomile or peppermint for a holistic approach to digestive and gut well-being.
FAQs
Our most common and readily available stock spec contains 15 billion CFU per gram. Other popular potencies include 30 billion, and 100 billion CFU/g. Higher concentrations up to 200 billion CFU/g are available with 8–10 week lead time for this ultra-stable probiotic.
Available in 5 kg, and 25 kg food-grade aluminum foil bags. MOQ is 5 kg regular production orders of this heat-stable probiotic. Small sample sizes are available as well.
Yes. We routinely supply ready-to-use premixes with prebiotics (inulin, chicory root extract, FOS), and other strains to simplify your manufacturing process for this formulation-friendly probiotic.
Under normal storage (≤25 °C, low humidity), ≤0.5 log loss over 36 months. Typical overage needed is only 10–20 %, thanks to its naturally encapsulated spore structure.
No. This shelf-stable probiotic is fully moisture-stable and ultra-stable, requiring no refrigeration at any stage—warehouse, transport, or finished product—while maintaining viability through GI transit.
Yes. Real-time and accelerated data show excellent survival in baking (up to 180–200 °C for muffins, cookies, granola bars, cereals), extrusion, retort, and high-pressure processing without microencapsulation.
Absolutely. This pH-stable probiotic remains viable down to pH 2.5–3.0 with minimal loss over 18–24 months in acidic environments like juices, smoothies, kombucha, coffee, tea, or gummies, without altering taste, aroma, or appearance.
Certificate of Analysis (CFU count, pathogens, heavy metals), Allergen Statement, GMO status, Kosher certified documentation, Halal certificates, BSE/TSE-free declaration, and stability summary for this clean-label probiotic. Additional GMP documents available upon request.
Standard production is non-GMO; Non-GMO Project Verified documentation is available. Organic-compliant fermentation can be arranged with 12–16 week lead time for this Kosher certified bulk ingredient.
Stock potencies ship in 3–7 business days or within 3-4 weeks if we are between incoming shipments. Custom blends or potencies: 8–12 weeks. Free formulation and stability support from our PhD team is included with every order, ideal for applications in dairy, non-dairy fermented products like yogurt, cheese, kefir, plant-based alternatives, savory items, capsules, tablets, powders, stick packs, softgels, and oral drops.