bacillus coagulans unique is2

Bacillus coagulans Unique IS‑2® – Clinically Proven, Ultra-Stable Probiotic

Your go-to strain for superior digestive, immune and functional performance in all product formats—no microencapsulation needed.

Nutrient Innovations, Inc. is a proud authorized US distributor for Bacillus coagulans Unique IS-2®. Recognized for its safety and extensively documented benefits, Bacillus coagulans Unique IS-2® is a gram‑positive, spore‑forming probiotic known for its exceptional resilience and scientific validation.

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A Unique Probiotic

Why Unique IS‑2 Stands Apart from Other Probiotics

This strain has received US FDA GRAS approval, distinguishing it as one of the few strains recognized by the U.S. Food and Drug Administration for its safety and efficacy. Additionally, it holds Health Canada-approved health claims and National Product Number (NPN) registration, underscoring its reliability and adherence to stringent regulatory standards. Bacillus coagulans Unique IS-2® is DNA tested for authenticity and proudly Kosher certified. Bacillus coagulans Unique IS-2® is not just a probiotic; it’s a holistic solution supported by an impressive 25 clinical studies, demonstrating its efficacy in enhancing various bodily functions. From promoting gut health, oral health, and immune health to aiding in weight management, diabetic support, and even benefiting our canine companions’ gut health, this strain has proven its versatility in fostering overall well-being.

Clinically Researched Health Benefits of Unique IS‑2

Digestive Health Reinvented

  • Promotes healthy digestion by balancing intestinal flora and improving gut microbiota diversity
  • Clinically shown to improve bowel regularity, reduce bloating, and ease abdominal discomfort
  • Supports relief from constipation and irregular stools with no reported side effects in trials
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Immune Health Fortification

  • Enhances natural immunity by stimulating protective cytokines and immune signaling pathways
  • Supports anti-inflammatory responses and improves gut-barrier integrity
  • Backed by clinical trials demonstrating improved host resistance to common infections
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Empowering Sports Nutrition & Fitness

  • Enhances protein absorption with an increase in total plasma-free amino acids for optimal sports nutrition.
  • Increase in leg press strength.
  • Improvement in vertical jump power.
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Unique IS-2® Food Applications

Bacillus coagulans Unique IS‑2® integrates seamlessly into a wide variety of food and supplement applications thanks to its exceptional resilience to heat, pH, and moisture. Whether incorporated into high-temperature baking processes, cold beverages, dairy products, or functional snacks, IS‑2 retains stability without requiring refrigeration or microencapsulation. Its spore-forming nature ensures excellent survivability through manufacturing, storage, and digestion—making it ideal for innovative formulations across health categories.

Baked Goods

Easily incorporated into muffins, cookies, granola bars, and cereals—retains viability through high-temperature baking.

Dairy & Non-Dairy Fermented Products

Compatible with yogurt, cheese, kefir, and plant-based alternatives—supports both live cultures and shelf-stable options.

Functional Beverages

Survives acidic, cold, or hot beverages including juices, smoothies, kombucha, coffee, and tea—without altering taste, aroma, or appearance.

Savory Applications

Compatible with yogurt, cheese, kefir, and plant-based alternatives—supports both live cultures and shelf-stable options.

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Unique IS-2 in Nutraceuticals

Bacillus coagulans Unique IS‑2® is a formulation-friendly probiotic ideal for a wide range of nutraceutical applications. Its naturally encapsulated spore structure allows it to survive manufacturing processes, shelf storage, and gastrointestinal transit without the need for refrigeration or protective coatings. This makes it highly compatible with diverse supplement delivery systems including capsules, tablets, powders, gummies, and liquid suspensions. Whether used as a standalone probiotic or combined with complementary ingredients like digestive enzymes, botanicals, or prebiotics, Unique IS‑2 offers reliable stability, clean-label appeal, and science-backed efficacy across consumer health categories.

Capsules & Tablets

Ideal for standalone probiotics or synergistic blends—maintains viability throughout GI transit and shelf life.

Powders & Stick Packs

Perfect for sachets, single-serve powders, and blends with prebiotics or digestive enzymes—easy to mix and consumer-friendly.

Softgels & Gummies

Stable without refrigeration, enabling inclusion in chewables, softgels, and gummies without sensory or stability compromises.

Oral Drops & Suspensions

Well-suited for liquid delivery in pediatric, geriatric, or pet supplements—retains potency in aqueous environments.

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Ingredients Synergizing with Bacillus coagulans Unique IS-2®

Probiotic Powerhouses

Combine with high-quality prebiotics such as inulin or chicory root extract for enhanced probiotic potency.

Nutrient Boosters

Pair with vitamin D3 for amplified immune health support, creating a robust foundation for overall wellness.

Omega-3 Fatty Acids

Formulate with omega-3-rich ingredients like fish oil to promote heart health in a comprehensive manner.

Herbal Allies

Blend with herbal extracts like chamomile or peppermint for a holistic approach to digestive and gut well-being.

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